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自由基病理学是讨论细胞中失控的异常的自由基反应所引起的病理学变化,这些反应可以由生理条件下产生的自由基所引起的,也可以由外源性化学剂所引起。这些化学剂或者本身就是自由基,或者可通过代谢形成自由基,或者是将正常细胞成分诱发为自由基。电离辐射是属于物理性致自由基剂。自由基独特的化学性质及其有关的分子构形的改变是自由基病理学的基础。细胞内大分子聚合物核酸和
Free radical pathology is a discussion of the pathological changes caused by abnormal uncontrolled free radical reactions in cells that can be caused by free radicals produced under physiological conditions and by exogenous chemicals. These chemicals are either free radicals themselves or they can be metabolized to free radicals or induce normal cellular components to become free radicals. Ionizing radiation belongs to the class of free radical agents. The unique chemical nature of free radicals and their associated molecular configuration changes are fundamental to free radical pathology. Intracellular macromolecular polymer nucleic acid and