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用表达harpin基因的大肠杆菌DHS进行了诱导植物抗病性的研究，发现表达harpin基因的重组菌除可明显诱发烟草、番茄叶片的过敏反应外，对玉米、水稻叶片也可诱发过敏反应，反应比相应阳性对照病菌速度快，坏死斑也更典型。用DHS菌悬液喷雾或注射诱导后，番茄对早疫病、水稻对稻瘟病、玉米对大、小斑病、马铃薯对软腐病的抗性均有不同程度的提高，与水杨酸诱导的抗性效果相当或比其略高。
The study of plant disease resistance induced by E. coli DHS expressing harpin gene showed that the recombinant strain expressing harpin gene could induce anaphylactic reaction on leaves of corn and rice in addition to the hypersensitive response of tobacco and tomato leaves. Faster than the corresponding positive control bacteria, necrotic spots are more typical. The resistance of tomato to early blight, rice blast, maize to large and small spot, potato to soft rot was induced by spray or injection of DHS bacterial suspension, which was different from salicylic acid induced The resistance is equivalent to or slightly higher than that.