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我们检测1例伴CD56高表达的巨核细胞白血病（M7）患儿，其免疫表型为CD41+（37．1％），CD56+（88．2％）；细胞遗传学显示亚二倍体增多；细胞化学染色结果：髓性过氧化物酶（－），苏丹黑B染色（－），特异性脂酶染色（－），非特异性脂酶（－）且不被FNa抑制，糖原染色弱阳性；骨髓中的幼稚细胞在体外有较高的NK细胞介导的细胞毒活性，此细胞经倍体分析发现，85．8％为二倍体细胞，证明它们属于不分化或分化很差的巨核细胞。
We detected 1 case of megakaryocytic leukemia (M7) with high expression of CD56 in children with an immunophenotype of CD41+ (37.1%) and CD56+ (88.2%); cytogenetics showed an increase in hypodiploid cells; Chemical staining results: myeloperoxidase (-), Sudan Black B staining (-), specific lipase staining (-), non-specific lipase (-) and not inhibited by FNa, glycogen staining weakly positive; The naive cells in the bone marrow have high NK cell-mediated cytotoxic activity in vitro. The cells were analyzed by ploidy analysis. 85.8% of them were diploid cells, which proved that they belong to undifferentiated or poorly differentiated megakaryocytes. .