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目的：评价3.0T磁共振增强多回波磁敏感加权成像（SWI）序列的磁敏感效应评价对胶质瘤分级的指导意义。方法16例成年脑肿瘤患者（低级别胶质瘤7例，高级别胶质瘤9例）于西门子3.0T磁共振扫描仪上行常规磁共振平扫及增强扫描、磁敏感加权成像增强扫描。选择显示脑肿瘤的最大横断面的SWI最小密度投影（mIP）图像作为标准图像对所示磁敏感效应程度进行评估。由两名经验丰富的中枢神经系统影像诊断医师针对逐个病例SWI mIP图像显示的肿瘤内磁敏感效应（ITSS）进行分级。结果高级别胶质瘤患者增强SWI mIP图像所示的ITSS平均评分结果为（2.2778±0.7519），低级别胶质瘤患者增强SWI mIP图像所示的ITSS平均评分结果为（1.2143±1.1217）。高、低级别胶质瘤患者增强SWI mIP图像的ITSS评分结果编秩后，Mann-Whitney U检验结果显示，高级别胶质瘤组与低级别胶质瘤组增强SWI mIP图像的ITSS评分结果差异具有统计学意义。结论高、低级别胶质瘤患者的增强SWI mIP图的ITSS分级结果差异具有统计学意义，增强SWI的mIP图像中ITSS分级对胶质瘤的分级具有重要的指导意义。“,”Objective To explore the value of contrast enhanced susceptibility weighted imaging (SWI) in 3.0 T for grading of gliomas.Methods16 adults with gliomas (7 for low-grade gliomas, 9 for high-grade gliomas) confirmed by craniotomy surgery and histopathology underwent conventional MRI, contrast enhanced T1WI and SWI. Magnitude maps and phase maps were acquired separately. Filtering of phase maps, reconstruction of SWI maps and minimum intensity projection were accomplished in the software SPIN. The maximum transverse sections images of the masses were collected as the standard images. Intratumoral susceptibility signal intensity (ITSS) was graded by two senior radiologists respectively. Results The average ITSS score of high-grade gliomas was (2.2778±0.7519). The average ITSS score of low-grade gliomas was (1.2143±1.1217).Mann-Whitney U test showed the signifi cant difference of ITSS between high-grade and low-grade gliomas.Conclusion ITSS between high-grade and low-grade gliomas has signifi cant difference. Contrast enhanced SWI can be used to assist grading of gliomas.