患儿男,1.5岁。因指端感染破溃久治不愈入院。患儿生后4个月,其母发现其面部常自行抓伤出血而无哭闹。6个月后,玩耍时身上常有碰伤、刺伤或烫伤,并常将指、趾放于口中玩咬出血。开始其母认为是坏习惯,后发现患儿右手指、食、中指末节逐渐被咬掉,其他指、趾端亦被咬伤,而患儿无任何疼痛表现。近3个月来伤指感染破溃逐渐加重而来院就诊。既往无内脏痛史。父母为姑表婚配。查体:体温36.1℃,脉搏100次/分,轻度贫血貌,表情痴呆,前额略呈方形,瞳孔等大,无眼球震颤及斜视。心肺腹无异常所见。四肢活动自如,右手拇、食、中指远节缺如,残端感染化脓破溃,其余指、趾端可见伤痕及新鲜创面。颅神经、眼底(-)。四肢肌力正常,肌张力略减低,四肢腱反射低下,且双侧等叩。共济运动协调。全身痛觉消失,温度觉减 Children male, 1.5 years old. Due to the end of infection ulceration chronic illness admitted to hospital. Four months after birth, her mother found her face often scratch bleeding without crying. After 6 months, the body often bruises, stabs or burns when playing, and often refers to the toe, put in the mouth to play biting bleeding. The mother began to think it is a bad habit, found that children with the right finger, food, middle finger gradually bite off the other means, toe is also bitten, but no pain in children with performance. In the past 3 months, the injured fingers gradually increased and they came to the hospital for treatment. No history of visceral pain. Parents for Gugu table marriage. Physical examination: body temperature 36.1 ℃, pulse 100 beats / min, mild anemia appearance, dementia, forehead slightly square, pupils and other large, no nystagmus and strabismus. No abnormal heart and lung seen. Limb movements, right hand thumb, food, missing from the middle finger, stump infection purulent rupture, the remaining fingers, toes visible scars and fresh wounds. Cranial nerve, fundus (-). Limb muscle strength is normal, slightly reduced muscle tension, limb tendon reflexes, and bilateral knocking. Masonic Movement Coordination. Body pain disappeared, temperature decrease