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目的分析IVF-ET中完全来源0PN卵裂期胚胎新鲜移植周期的妊娠结局,评价0PN卵裂期胚胎临床应用价值。方法回顾性调查2011年8月至2013年11月在安徽省妇幼保健院生殖中心接受IVF-ET治疗中21个完全来源0PN的卵裂期胚胎新鲜移植周期,分析其临床妊娠情况。结果 21个完全来源0PN的卵裂期胚胎新鲜移植周期中临床妊娠6例(9胎),其中3例活产(3男2女),2例流产(3胎),1例异位妊娠。结论 IVF-ET新鲜移植周期中在没有来源2PN正常受精的卵裂期胚胎时,可慎重选择来源0PN的卵裂期胚胎进行胚胎移植。
OBJECTIVE: To analyze the pregnancy outcome of 0PN cleavage stage complete embryos in IVF-ET and to evaluate the clinical value of 0PN cleavage stage embryos. Methods A retrospective study was conducted between August 2011 and November 2013 in fresh reproductive cycles of 21 complete 0PN cleavage stage embryos in the Reproductive Center of Anhui Provincial MCH Center for IVF-ET. Clinical pregnancy status was analyzed. Results Sixty-one clinical pregnancies (9 pregnancies) were obtained during 21 fresh-sourced 0PN cleavage stage embryos, of which 3 were alive (3 males and 2 females), 2 were aborted (3) and 1 was ectopic. Conclusions In the absence of new stage 2FN fertilized cleaved embryos during the IVF-ET fresh transplantation cycle, 0PN cleavage stage embryos can be carefully selected for embryo transfer.