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观察内皮及内源性一氧化碳 (ＣＯ)合成酶抑制剂 (血红素氧化酶抑制剂ＺｎＰＰＩＸ)对大鼠缺氧性肺血管收缩反应的影响 ,探讨内源性ＣＯ在缺氧性肺血管收缩反应中的作用。制备Ｗｉｓｔｅｒ大鼠肺动脉环 ,观察内皮与缺氧性肺血管收缩反应的关系 ,并以一氧化氮合成酶抑制剂Ｌ -Ｎ?
To observe the effect of endothelial and endogenous CO synthase inhibitor (heme oxygenase inhibitor ZnPPIX) on hypoxic pulmonary vasoconstriction in rats and to explore the role of endogenous CO in hypoxic pulmonary vasoconstriction Role. Pulmonary artery rings of Wister rats were prepared and the relationship between endothelium and hypoxic pulmonary vasoconstriction was observed. Nitric oxide synthase inhibitor L -N