郑××,女性,19岁,住院号167132。因右面部巨型肿块,严重狮面畸形10余年,伴说话,吞咽和右眼视力障碍一年,于1972年3月14日入院。过去史及家庭史无特殊。月经正常。体查:见躯干、四肢有散在性褐色素沉着斑,背部大片毛细血管扩张。颌面肿块以右侧为主,延及左侧,约30×30×18厘米大小,边界不清,与皮肤不能分开,皮肤浅褐色(图1、2)。右眼突出度3.5厘米(眼距9厘米),双眼球上下彼此相差3.5厘米,右上睑穹窿深4厘米,上下睑极度肥厚,撑开后,见结合膜慢性充血,水肿,角膜周边略混浊,瞳孔中等散大,光反应迟钝,视力眼前数指。外鼻极度肥厚,并向左下移位,鼻中隔极度偏左,右侧3/4之硬软腭亦肿胀增生,向左推移,下颌双侧不对称,呈明显倾斜状。(?)缺失,(?)残冠,口腔粘膜亦有点状褐色素 Zheng ××, female, 19 years old, hospital number 167132. He was admitted to the hospital on March 14, 1972 due to a massive mass on his right face, severe lion malformation for more than 10 years, speech, swallowing, and vision impairment in the right eye for one year. There is no special history or family history. Menstruation is normal. Physical examination: See trunk, limbs with scattered brown spots, large telangiectasias on the back. The maxillofacial masses are mainly rightward and extend to the left, about 30×30×18 cm in size, with unclear borders, inseparable from the skin, and light brown skin (Figures 1, 2). Right eye protrusion 3.5 cm (eye distance 9 cm), eyeballs up and down 3.5 cm apart, right upper eyelid 4 cm deep, extreme hypertrophy of the upper and lower jaw, open, see the conjunctival chronic congestion, edema, slightly turbid around the cornea, The pupil is moderately scattered, the photoreaction is slow, and the number of eyes is just before the eyes. The external nose was extremely hypertrophic and shifted to the lower left. The nasal septum was extremely leftward. The hard palate on the right side was also swollen and hyperplastic with a leftward shift. The mandible was bilaterally asymmetrical, showing a pronounced tilt. (?)miss, (?) residual crown, oral mucosal brownish pigment