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目的比较童便、男性成人尿液、纯水及黄酒对生化汤煎剂中阿魏酸溶出量的影响。方法不同溶剂进行生化汤的煎煮,利用反相高效液相法检测煎剂中阿魏酸的含量。结果童便组0.5倍处方量生化汤煎剂中含阿魏酸的量为(16.73±0.12)mg,成人组为(11.76±0.06)mg,纯水组为(13.98±0.07)mg,黄酒组为(12.99±0.13)mg。结论童便组阿魏酸的含量明显高于其他组(P<0.01)。
Objective To compare the effects of Tongbian, male adult urine, pure water and rice wine on the dissolution of ferulic acid in Biochemical Decoction. Methods Different solvents were used to decoction of biochemical soup, and the contents of ferulic acid in decoctions were determined by RP-HPLC. Results The amount of ferulic acid in Tongxuetang decoction was 0.57 times that of Tongbu Decoction group (16.73 ± 0.12) mg, (11.76 ± 0.06) mg in adult group and (13.98 ± 0.07) mg in pure water group (12.99 ± 0.13) mg. Conclusion The content of ferulic acid in Tongbian group is obviously higher than other groups (P <0.01).