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目的比较妊娠期亚临床甲状腺功能减退孕妇及甲状腺功能正常孕妇的血压变化,探讨妊娠期亚临床甲状腺功能减退对血压的影响。方法收集2008年1月～2010年12月妊娠期亚临床甲状腺功能减退及甲状腺功能正常孕妇各80例,监测妊娠期血压变化情况,并计算高血压的患病率。结果妊娠期亚临床甲状腺功能减退组收缩压及舒张压均高于甲状腺功能正常组(t收缩压=2.73,P﹤0.01;t舒张压=4.42,P﹤0.01),前者的高血压患病率也明显高于后者(χ2=4.25,P﹤0.05)。结论妊娠期亚临床甲状腺功能减退可能是妊娠期高血压的独立危险因素。
Objective To compare the changes of blood pressure in pregnant women with subclinical hypothyroidism during pregnancy and normal pregnant women with normal thyroid function and to explore the influence of subclinical hypothyroidism during pregnancy on blood pressure. Methods A total of 80 pregnant women with subclinical hypothyroidism and normal thyroid function during pregnancy were collected from January 2008 to December 2010. The changes of blood pressure during pregnancy were monitored and the prevalence of hypertension was calculated. Results Systolic and diastolic blood pressure in subclinical hypothyroidism during pregnancy was significantly higher than that in patients with normal thyroid function (t systolic pressure = 2.73, P <0.01; t diastolic pressure = 4.42, P <0.01) Also significantly higher than the latter (χ2 = 4.25, P <0.05). Conclusion Subclinical hypothyroidism during pregnancy may be an independent risk factor for gestational hypertension.