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本实验采取琼脂平板稀释法测定了泰宁等７种抗菌药物对５种２ｌ５株临床常见致病菌的最低抑菌浓度（ＭＩＣ），并统计了敏感率，结果表明７种抗菌药物对大多数受试菌均显示了较高的抗菌活性，其中泰宁的抗菌活性最强。金黄色葡萄球菌、变形杆菌、大肠埃希氏菌、肺炎克雷白氏菌对泰宁的敏感率达９７．６～１００％；１７．０２％的绿脓假单胞菌耐药，４．２６—１２．７７％绿脓假单胞菌和１株肺炎克雷白氏菌对泰宁和其他抗菌药物呈现部分交叉耐药性，而ＣＰＦＸ与其他抗菌药物对不同受试菌呈现２．３８～１９．０５％的交叉耐药率，该结果提示对其他β－内酰胺类抗菌药物耐药的致病菌引起的严重感染，可考虑选用泰宁，但ＣＰＦＸ的选用还应根据药敏试验决定。
In this experiment, the minimum inhibitory concentration (MIC) of 7 kinds of antibiotics such as Taining on five kinds of 2l5 clinical common pathogens was determined by agar plate dilution method, and the sensitivity rate was calculated. The results showed that seven kinds of antibacterial drugs The tested bacteria showed higher antibacterial activity, of which Taining strongest antibacterial activity. Staphylococcus aureus, Proteus, Escherichia coli, Klebsiella pneumoniae sensitivity of Taining 97.6 ~ 100%; 17.02% Pseudomonas aeruginosa drug-resistant, 4. 26-12.77% of Pseudomonas aeruginosa and 1 strain of Klebsiella pneumoniae exhibited partial cross-resistance to Taining and other antibacterials while CPFX and other antibacterials showed 2.38 ~ 19.05% of the cross-resistance rate, the results suggest that other β-lactam antibiotics-resistant pathogens caused by serious infection, consider the selection of Taining, but CPFX selection should also be based on susceptibility testing Decided.