尽管垂体腺瘤是良性的 ,但其中相当多的肿瘤侵袭垂体以外的组织结构。侵袭性垂体腺瘤的治疗依然面临挑战 ,导致侵袭倾向的生物学因素仍不清楚 ,仅凭临床症状、影像学特点和组织类型难以反映其生物学行为特征。目前临床实验研究表明 ,癌基因、抑癌基因、增殖细胞核抗原 ,蛋白激? Although pituitary adenomas are benign, a considerable number of them invade the pituitary tissue structure. The treatment of invasive pituitary adenomas is still challenged, the biological factors leading to invasion are still not clear, based solely on clinical symptoms, imaging features and types of tissues difficult to reflect the biological behavior characteristics. The current clinical trials show that oncogenes, tumor suppressor genes, proliferating cell nuclear antigen, protein kinase?