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目的了解不同水碘地区成人碘营养状况和甲状腺相关疾病患病情况。方法采用多阶段随机抽样法,对天津市不同水碘地区506名调查对象进行B超检查、甲状腺生化指标检测和尿碘检测;采集并检测居民户盐样、所在行政村(居委会)水样。结果高碘地区水碘中位数155.7μg/L,非高碘地区水碘中位数8.0μg/L。高碘地区食用无碘食盐,非高碘地区食用加碘食盐,盐碘中位数23.30mg/kg。高碘地区成人尿碘中位数168.10μg/L大于非高碘地区146.20μg/L(P=0.048),均处于适宜水平;非高碘地区TGAb、TPOAb阳性率(22.5%、19.3%)均高于高碘地区(11.8%、9.8%);慢性淋巴细胞性甲状腺炎患病率为高碘地区(5.02%)>非高碘地区(1.03%);甲状腺结节患病率为高碘地区(32.48%)>非高碘地区(15.09%)。结论高碘地区成人甲状腺结节、慢性淋巴细胞性甲状腺炎患病率要高于非高碘地区,应引起重视。
Objective To understand the status of adult iodine nutrition and thyroid-related diseases in different areas of iodine. Methods The multistage random sampling method was used to carry out B-ultrasound, thyroid biochemical detection and urine iodine test on 506 subjects in different areas of iodine in Tianjin. Samples of salt samples of residents and the water samples of administrative villages (neighborhood committees) were collected and tested. Results The median iodine-iodine water iodine concentration was 155.7 μg / L and the non-iodine iodine water iodine concentration was 8.0 μg / L. Iodine consumption of iodine-free salt, iodine non-iodized area consumption of iodized salt, salt iodine median 23.30mg / kg. The median urinary iodine concentration in adults with high iodine concentration was 168.10μg / L, which was higher than that in non-iodine region (146.20μg / L, P = 0.048), and the positive rates of TGAb and TPOAb in non-iodine region were 22.5% and 19.3% (11.8%, 9.8%). The prevalence of chronic lymphocytic thyroiditis was high iodine (5.02%) and non-iodine (1.03%). The prevalence of thyroid nodules was high iodine (32.48%)> non-iodine region (15.09%). Conclusions The prevalence of thyroid nodules and chronic lymphocytic thyroiditis in high-iodine area is higher than that in non-iodine area, which should be paid more attention.