论文部分内容阅读
目的比较左乙拉西坦与托吡酯治疗小儿癫痫的临床疗效。方法选取南充市中心医院2014年2月—2016年2月收治的癫痫患儿88例,采取随机数字表法分为对照组和研究组,各44例。对照组患儿给予托吡酯治疗,研究组患儿给予左乙拉西坦治疗。比较两组患儿临床疗效及不良反应发生情况。结果研究组患儿临床疗效与对照组相当,差异无统计学意义(P>0.05)。两组患儿不良反应发生率比较,差异无统计学意义(P>0.05)。结论左乙拉西坦与托吡酯治疗小儿癫痫均具有良好的临床效果,且不良反应少,安全性高,因此临床可根据患儿的实际病情选择合适的药物,以达到最佳的治疗效果。
Objective To compare the clinical efficacy of levetiracetam and topiramate in the treatment of children with epilepsy. Methods Eighty-eight children with epilepsy admitted from February 2014 to February 2016 in Nanchong Central Hospital were randomly divided into control group and study group, with 44 cases in each group. The control group was given topiramate, and the study group was given levetiracetam. The clinical efficacy and adverse reactions of the two groups were compared. Results The clinical efficacy of the study group was similar to that of the control group, with no significant difference (P> 0.05). There was no significant difference in the incidence of adverse reactions between the two groups (P> 0.05). Conclusion Levetiracetam and topiramate treatment of children with epilepsy have a good clinical effect, and adverse reactions, high safety, so the clinical according to the actual condition of children choose the appropriate drug in order to achieve the best therapeutic effect.