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对 2 1名单纯性肥胖少年儿童及 16名正常健康少年儿童的部分免疫指标进行了检测 (T淋巴细胞亚群采用APAAP法 ,NK细胞活性选用LDH释放法 ) ,并对 7名单纯性肥胖少年儿童进行了 10周的耐力训练。结果 :肥胖少儿的CD4+/CD8+、NK活性显著降低 (p <0 0 5 )。CD8+较正常少儿高 ,但无显著性差异 ,白细胞数、中性粒细胞数、淋巴细胞数、CD3+、CD4+、CD16 +、CD56 +两组接近 ;10周耐力训练后 ,肥胖少年儿童的CD4+/CD8+、NK活性显著提高 (p <0 0 5 ) ,CD4+有所提高 ,CD8+有所下降 ,但无显著性差异 ;白细胞数、中性粒细胞数、淋巴细胞数、CD3+、CD16 +、CD56 +无显著性改变。结果表明 :单纯性肥胖少年儿童的免疫功能受损 ,耐力运动能改善肥胖少年儿童的免疫功能。提示单纯性肥胖少年儿童的免疫功能受损与体脂的改变和血脂质代谢紊乱有关。
A total of 21 immunosuppressive children with idiopathic obesity and 16 normal healthy children were tested for partial immune markers (T lymphocyte subsets by APAAP method, NK cell activity by LDH release method), and 7 simple obese adolescents Children undergo 10 weeks of endurance training. Results: The obese children had significantly lower CD4 + / CD8 + and NK activities (p <0.05). CD8 +, CD8 +, CD16 + and CD56 + were close to each other. After 10 weeks of endurance training, the percentage of CD4 + / CD8 + CD8 +, NK activity were significantly increased (P <0 05), CD4 + increased, CD8 + decreased, but no significant difference; white blood cell count, neutrophil count, lymphocyte count, CD3 +, CD16 +, CD56 + No significant change. The results showed that the immune function of juvenile simple obese children impaired, endurance exercise can improve the immune function of obese children. Tip simple obesity in children with impaired immune function and body fat changes and lipid metabolism disorder related.