庆大霉素属氨基糖甙类抗生素,其抗菌谱广,对革兰氏阴性菌或阳性菌都具良好的抗菌作用。自1969年问世以来,临床应用日趋广泛,并被我国列为“基本药物”之一。据某县医药公司统计:该县庆大霉素注射剂的销售量,1982年比1981年增长43.8%;比1973年增长70倍,增长速度在抗生素类药物中十分突出。可是,由于某些医务人员对庆大霉素缺乏全面的认识,以为其“完全可以替代青霉素G作为消炎退热的万能药”。因此在临床应用上出现许多不合理的现象,给病人的健康造成危害,甚至危及生命。为了合理的应用庆大霉素,必须了解其抗菌作用、毒性及临 Gentamycin is an aminoglycoside antibiotic, its broad antibacterial spectrum, against Gram-negative bacteria or positive bacteria have a good antibacterial effect. Since its publication in 1969, its clinical application has become increasingly widespread and has been listed as one of the “essential medicines” in our country. According to a county pharmaceutical company statistics: sales of gentamicin injection in the county in 1982 increased 43.8% over 1981; 70 times more than in 1973, the growth rate of antibiotics is very prominent. However, due to the lack of a comprehensive understanding of gentamicin by some medical staff, it is thought that “it can completely replace penicillin G as a panacea for anti-inflammatory and antipyretic effects.” Therefore, there are many unreasonable phenomena in clinical application, which may endanger the health of patients and even endanger life. In order to apply gentamicin reasonably, it is necessary to understand its antibacterial effect, toxicity and toxicity