应用药物治疗新生儿呼吸暂停已达十年之久。1973年首次报导新生儿直肠灌注茶碱可减少呼吸暂停发作,此后许多研究肯定了甲基黑嘌呤类药物的疗效,与之关系密切的咖啡因随之也广泛而有效地应用于临床。近来,Alpan等又对甲基黄嘌呤类有耐药的患儿应用呼吸兴奋剂盐酸吗乙苯吡酮(Doxapram)感到兴趣。更新的呼吸兴奋剂Almitrine,也有类似作用。药物治疗呼吸暂停仅用于明确诊断的患 Application of medication for neonatal apnea has been ten years. The first report in 1973, neonatal rectal perfusion of theophylline can reduce the onset of apnea, since then many studies affirmed the efficacy of methyl-purine drugs, followed by caffeine is also widely and effectively applied to clinical. Recently, Alpan et al have also shown interest in methylxanthine-resistant children using the respiratory stimulant Doxapram. The updated respiratory stimulant Almitrine also has a similar effect. Medication Apnea is only used to confirm the diagnosis of the disease