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目的:观察参芪血府逐瘀汤治疗冠心病气虚血瘀型的临床疗效及对血脂、血液流变学等的影响。方法:将100例患者随机分为治疗组和对照组各50例,对照组采用西药常规治疗,治疗组在对照组治疗的基础上同时加服参芪血府逐瘀汤每天1剂,水煎分2次服,疗程4周,分别观察治疗前后两组患者心绞痛症状、心电图、血脂、血液流变学变化情况,并观察临床症状改善情况。结果:心绞痛疗效,总有效率治疗组为96.0%,对照组为74.0%,两组比较差异有显著性意义(P<0.05);中医症候总疗效,治疗组为96.0%,对照组为62.0%,两组比较差异有非常显著性意义(P<0.01);治疗后治疗组血脂、血液流变学改善与对照组对比,差异有非常显著性意义或显著性意义(P<0.01,P<0.05)。结论:参芪血府逐瘀汤治疗冠心病气虚血瘀型不仅能改善临床症状,并能显著降低血脂,改善血液流变学的异常,取得较好的临床疗效。
Objective: To observe the clinical efficacy of Shenqi Xuefu Zhuyu Decoction in treating coronary heart disease with qi deficiency and blood stasis syndrome and its effects on blood lipids, hemorheology and so on. Methods: 100 patients were randomly divided into treatment group and control group of 50 cases, the control group with conventional Western medicine treatment group in the control group based on the same time plus Senate Xuefu Zhuyu Tang 1 day, decoction The patients were divided into 2 times and given for 4 weeks. The changes of angina pectoris, electrocardiogram, blood lipids and hemorheology in the two groups were observed before and after treatment, and the clinical symptoms were observed. Results: The total effective rate of angina pectoris was 96.0% in the treatment group and 74.0% in the control group, with significant difference between the two groups (P <0.05). The total curative effect of TCM was 96.0% in the treatment group and 62.0% in the control group , There was significant difference between the two groups (P <0.01). After treatment, the improvement of blood lipid and hemorheology in the treatment group was significantly different from the control group (P <0.01, P <0.05) ). Conclusion: Shenqi Xuefu Zhuyu Decoction in treating coronary heart disease with qi deficiency and blood stasis not only can improve clinical symptoms, but also can significantly lower blood lipids, improve hemorheology abnormalities and achieve better clinical curative effect.