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目前,抗生素在呼吸科应用非常广泛,但近年来,抗生素从广泛使用演变成过量使用甚至滥用。盲目、不合理用药的不良后果是导致不良反应增多,细菌耐药性增长,治疗失败等,给患者的健康和生命造成重大影响。如何合理使用抗生素已是目前迫切需要解决的问题。本文从病原学诊断、正确选用抗生素、联合用药、根据生理病理和免疫等状态合理用药、考虑血药有效浓度、注意配伍禁忌及掌握给药途径等方面进行了分析,以期临床合理用药。
Currently, antibiotics are widely used in respiratory department, but in recent years, antibiotics have evolved from extensive use to overuse and even abuse. Blind, irrational use of drugs adverse consequences lead to increased adverse reactions, increased bacterial resistance, treatment failure, etc., to the patient’s health and life have a significant impact. How to use antibiotics reasonably is an urgent problem to be solved. In this paper, from the etiological diagnosis, the correct selection of antibiotics, combined medication, according to physiological and pathological and immunological status of rational use of drugs, taking into account the effective concentration of blood, attention to incompatibility and control of drug delivery methods were analyzed in order to clinically rational use of drugs.