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以不同剂量的环丙沙星（３皿ｕｇ·Ｋｇ－１及６００ｕｇｋｇ－１）注入大鼠右侧脑室后，于皮层感觉运动区记录皮层脑电图作脑电功率谱及频率分配分析。注射后两剂量组皮层均先后出现痫样放电（大剂量、小剂量组潜伏期分别为３５．３３±３５．１６和１５３．８８±９４．２１９）脑电功率谱及频率分配分析主要表现为总功率及脑电的快成分（ａ、β和β２）所占百分比增加而功率主峰频段δ波所占百分比减少。提示：环丙沙星对中枢神经系统具有兴奋作用。
After ciprofloxacin (3 μg · kg-1 and 600 μg · kg-1) was infused into right ventricle of rats, cortical EEG was recorded in the sensory zone of cortex and the frequency distribution was recorded. Epileptiform discharges occurred in the cortex of both groups after injection (the latency of high dose and low dose were 35.33 ± 35.16 and 153.88 ± 94.219, respectively) EEG power spectrum and frequency distribution analysis showed that the total power And the fast component (a, β and β2) of EEG increased while the percentage of δ wave in the power peak frequency band decreased. Tip: Ciprofloxacin has an exciting effect on the central nervous system.