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目的了解肺心病并多脏器功能损害的血气酸碱变化特点与预后的关系。方法回顾性分析84例肺心病并多脏器功能损害患者的临床资料。结果肺心病并多脏器功能损害的病死率为52.4%,发生损害的脏器或系统依次为脑、肾、肝、胃肠、血液。pH值愈低致酸血症越重、动脉血氧分压(PaO2)越低、动脉血二氧化碳分压(PaCO2)短期内迅速上升、脏器受损数目越多病死率越高。结论肺心病并多脏器功能损害的病死率随着脏器受损数目的增加而上升,与血气和酸中毒的恶化程度有关。发病期间应加强血气监测,重点防治呼吸衰竭。
Objective To understand the relationship between the characteristics of blood gas acid-base changes and prognosis in patients with pulmonary heart disease and multiple organ dysfunction. Methods A retrospective analysis of 84 cases of pulmonary heart disease and multiple organ dysfunction in patients with clinical data. Results The mortality rate of pulmonary heart disease and multiple organ dysfunction was 52.4%. The organs or systems that were damaged were brain, kidney, liver, stomach, intestine and blood. The lower the pH is, the more severe the acidosis is. The lower the PaO2 is, the shorter the PaCO2 is in the short term. The higher the number of organ damage is, the higher the mortality is. Conclusion The mortality of pulmonary heart disease with multiple organ dysfunction increased with the increase of the number of organ damage, which was related to the worsening of blood gas and acidosis. During the onset of blood gas monitoring should be strengthened, focusing on prevention and treatment of respiratory failure.