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近年来由于结肠癌发病率的显著增高,对其早期发现的普查工作已普遍引起重视。目前公认,检查便潜血反应是大规模集体普查结肠癌较简便易行的筛选方法,可在受检者中发现0.1%左右的结肠癌患者。但是传统的化学便潜血反应检查方法对人红细胞的血红蛋白不具有特异性,食物中的猪牛等动物血及蔬菜等都可呈现阳性反应,为提高其特异性必须禁食上述食物,但其假阳性率仍达32%。而在提高其特异性的同时,可使其敏感性相对下降,使少量出血者漏诊。
In recent years, due to the significant increase in the incidence of colon cancer, census work for its early detection has generally attracted attention. It is currently accepted that the detection of fecal occult blood reactions is a simple and easy screening method for large-scale collective screening of colon cancer. About 0.1% of colon cancer patients can be found in the subjects. However, traditional methods for detecting chemical occult blood reactions do not have specificity for hemoglobin of human erythrocytes. Animals such as pigs and cows in foods can exhibit positive reactions to blood and vegetables. In order to increase their specificity, these foods must be fasted, but their The positive rate is still 32%. While increasing its specificity, it can make its sensitivity relatively lower, so that a small amount of bleeding is missed.