2013年美国心脏病学学会/美国心脏协会血脂指南的发布在学界激起波澜,国内外众多学术组织相继发布文件阐明自己的观点。2016年,欧洲心脏病协会和中国血脂指南相继发表。3个指南在血脂管理上存在诸多不同,争论的焦点在于是否设立降脂靶目标以及如何强化,差异之处体现了各自对于血脂的独特理解。本文从这两点出发进行探讨。 In 2013 the American College of Cardiology / American Heart Association guidelines for lipid release in the academic turmoil, many domestic and foreign academic organizations have released documents to clarify their point of view. In 2016, the European Society of Cardiology and China’s lipid guidelines were published. There are many differences in blood lipid management among the three guidelines. The focus of the debate is whether to set goals for lipid-lowering targets and how to reinforce them. The differences reflect their unique understanding of blood lipids. This article starts from these two points.