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肉毒素是由肉毒杆菌分泌的一种神经毒素,肉毒素中毒可导致患者多器官功能障碍。6例患者均为女性,年龄25~55岁,注射肉毒素2~9d后出现中毒症状。临床表现为:眼睑下垂、吞咽困难、视物模糊、言语不清、肢体无力、呼吸困难及失眠伴焦虑不安等症状;其中1例出现Ⅱ型呼吸衰竭。所有患者给予抗感染、营养支持、抗焦虑及对症治疗,严重中毒患者行呼吸机辅助通气及血液灌流,均治愈出院。
Botulinum toxin is a neurotoxin secreted by Botox that causes multiple organ dysfunction in patients. All 6 patients were female, aged 25-55 years old. After 2 ~ 9 days of botulinum toxin injection, symptoms of poisoning were observed. Clinical manifestations: eyelid ptosis, swallowing difficulties, blurred vision, slurred speech, limb weakness, dyspnea and insomnia with anxiety and other symptoms; one case of type Ⅱ respiratory failure. All patients given anti-infective, nutritional support, anti-anxiety and symptomatic treatment, severe poisoning patients ventilator-assisted ventilation and hemoperfusion, were cured.