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目的:了解枣阳地区高三学生乙肝病毒感染状况,为乙肝的防治提供理论依据,保护学生的身体健康。方法:采用酶联免疫吸附实验(ELISA)对2002年-2009年枣阳地区58296名高三毕业学生进行乙肝表面抗原(HBsAg)的检测,并将结果进行统计分析。结果:2002年全地区高三学生乙肝表面抗原阳性率为8.3%,以后呈明显下降趋势,到2004年下降至6.53%,然后感染率保持在6.4%左右;2003年与2002年阳性率对比差别无统计学意义(χ2=1.54,P>0.05),2004年阳性率比2002年减少了1.85%,对比差别有统计学意义(χ2=13.58,P<0.01),随后五年阳性率对比差别无统计学意义(P>0.05),城市感染率低于乡村,对比差别有统计学意义(χ2=25.27,P<0.01)。结论:枣阳地区高三学生乙肝病毒感染率2002年-2004年三年内呈逐年下降势态,随后五年内维持在一个稳定水平,整个地区高三学生乙肝病毒感染率低于全国平均水平,其中农村感染率要高于城市,这应引起当地政府足够重视,加强农村基础医疗建设投入,提高对感染性疾病的防护水平。
Objective: To understand the status of hepatitis B virus infection in senior high school students in Zaoyang district and to provide a theoretical basis for the prevention and treatment of hepatitis B, and to protect the health of students. Methods: Enzyme linked immunosorbent assay (ELISA) was used to detect HBsAg in 58 296 graduates of senior high school students in Zaoyang from 2002 to 2009, and the results were statistically analyzed. Results: The positive rate of HBsAg in senior high school students was 8.3% in 2002, then decreased obviously to 6.53% in 2004, and the infection rate remained at 6.4%. The positive rate of positive rate in 2003 and 2002 was no difference (Χ2 = 1.54, P> 0.05). The positive rate in 2004 was 1.85% less than that in 2002, and the difference was statistically significant (χ2 = 13.58, P <0.01). There was no statistical difference in the positive rates after 5 years Significance of the study (P> 0.05), urban infection rate was lower than that of the rural areas, the difference was statistically significant (χ2 = 25.27, P <0.01). Conclusion: The prevalence of hepatitis B virus infection among senior high school students in Zaoyang was declining year by year in three years from 2002 to 2004, then maintained at a stable level within five years. The infection rate of hepatitis B virus among the third year students in the whole region was lower than the national average level. Among them, Which should be higher than that of the cities. This should arouse the local government enough attention to strengthen the investment in rural basic medical construction and improve the level of protection against infectious diseases.