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运用泻下与运动疲劳因素塑造大鼠脾气虚证模型。通过光镜、电镜观察和形态计量,对脾气虚证大鼠模型的骨骼肌细胞形态及肌细胞平均截面积、骨骼肌肌原纤维和线粒体体密度、线粒体面数密度进行观测。发现脾气虚与线粒体的结构异常和肌细胞的蛋白代谢负平衡相关。健脾益气的扶正健脾液对脾气虚证时的上述改变有良好的恢复作用。
Using diarrhea and exercise fatigue factors to establish the model of spleen - qi deficiency in rats. The morphology of skeletal muscle cells, the average cross-sectional area of myocytes and the myofibrillar and mitochondrial density of mitochondria and the number density of mitochondria were observed by light microscopy, electron microscopy and morphometry. Found that spleen deficiency and mitochondrial structural abnormalities and muscle cell protein metabolism negative balance. Spleen qi enrichment of the spleen qi deficiency on the above-mentioned changes have a good recovery.