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目的：了解泸州地区鲍曼不动杆菌的感染分布及耐药现状，为临床治疗提供依据。方法统计2010-2012年泸州地区5家综合性医院分离的鲍曼不动杆菌的来源、科室分布及药敏试验结果，应用WHONET5.4软件进行统计学分析。结果监测结果表明，检出率最高是痰（73.51%）和分泌物（10.08%），ICU和呼吸内科；头孢曲松、氨曲南、丁胺卡那霉素耐药率上升较快，超过了50%，差异有统计学意义；鲍曼不动杆菌对哌拉西林他唑巴坦钠、头孢哌酮钠舒巴坦钠、左氧氟沙星、环丙沙星和碳青霉烯类抗菌药物敏感率较高。结论泸州地区鲍曼不动杆菌耐药率有升高的趋势，应结合药敏试验结果选用抗菌药物。“,”Objective To understand the distribution characteristics and drug resistance of Acinetobacter baumanni in luzhoudistrit to provide a reference for clinical treatment.Methods The result of drug susceptibility and clinical distribution of Acinetobacter baumanni from five different hospital in luzhou area were analyzed and studied retrospectively.The antimicmbial resistance rates were analyzed by WHONET 5.4 software.Results Acinetobacter baumanni infection occurred in ICU or respiratorywards,which was detected from the specimens of sputum(73.51%) and secretion(10.08%).The resistance that over fifty percent were Ceftriaxone,Aztreonam and Amikacin.There high sensitivity in Piperacil intazobactam,Cefoperazone-euudbactam,Levofloxaein,Cipmfloxacinand carbapenems of Acinetobacter baumanni .Conclusion Acinetobacter baumanni has severe drug resistance in luzhou region,Proper antimicrobial drugs should be selected according to the results of drug susceptibility tests.