用免疫组化方法,观察大鼠在缺碘条件下,其脑垂体中 TSH,GH,LTH 细胞的形态及数量变化。结果发现,碘缺乏大鼠的脑垂体中 TSH 细胞明显肥大,出现所谓的去甲状腺细胞。其脑垂体中 GH细胞大多数较正常组的 GH 细胞直径小,其数量与正常组没有显著变化。其脑垂体中 LTH 细胞的形态及数量与正常组的 LTH 细胞无明显变化。 Immunohistochemistry was used to observe the morphological changes of TSH, GH and LTH in the pituitary of rats under iodine deficiency. The results showed that, TSH cells in the pituitary gland of iodine deficiency rats were significantly hypertrophy, the emergence of so-called goiter cells. The majority of GH cells in the pituitary gland were smaller in diameter than the GH cells in the normal group, and their numbers did not change significantly from those in the normal group. The morphology and number of LTH cells in the pituitary gland had no significant changes compared with those in the normal group.