论文部分内容阅读
α－触核蛋白是帕金森病(ＰＤ)等露易小体疾病的特征性病理变化中的主要成分之一。已经证实它的异常聚集和突变与ＰＤ的发病机制有关。α－触核蛋白的基因表达和转基因动物的研究,为此提供了一定的证据,也提示α－触核蛋白在ＰＤ发病机制中发挥重要的作用。
Alpha-synuclein is one of the major components in the characteristic pathological changes of Lewy body diseases such as Parkinson’s disease (PD). It has been confirmed that its abnormal aggregation and mutations are related to the pathogenesis of PD. Alpha-thaliana gene expression and transgenic animal research, to provide some evidence, but also suggests that alpha-synuclein play an important role in the pathogenesis of PD.