论文部分内容阅读
A novel and general carbon-nitrogen and carbon-carbon cross-coupling reaction between 3,4-dihydropyrimidine-2-thiones and copper(Ⅰ) carboxylates were performed in the presence of palladium acetate.The copper(Ⅰ) carboxylates act not only as desulfurative reagents but also as sources of carbon nudeophiles.A wide array of highly substituted and functionalized pyrimidines scaffolds were synthesized in good yields.
A novel and general carbon-nitrogen and carbon-carbon cross-coupling reaction between 3,4-dihydropyrimidine-2-thiones and copper (I) carboxylates were performed in the presence of palladium acetate. desulfurative reagents but also as sources of carbon nudeophiles. A wide array of highly substituted and functionalized pyrimidines scaffolds were synthesized in good yields.