论文部分内容阅读
目的:观察规范化血压管理与治疗对急性脑出血(基底节区)预后的影响,探讨分期和规范化管理血压的可行性。方法:对发病12h内入院的脑出血(基底节区)患者随机分组,记录患者95版中国脑卒中临床神经功能缺损程度评分量表(简C表)、斯堪的那维亚卒中量表(scandinavian stroke scale,SSS,简S表)神经功能评分的均数变化(入院、1周、2周、3个月),用“预先设定血压目标范围”和“分期、选药、联合、全面达标”原则控制血压(规范的血压管理治疗)为研究因素,比较治疗组(规范的血压管理治疗,n=41)与对照组(传统血压管理治疗,n=41)3个月内的转归变化。结果:①3个月内治疗组的病死率低于对照组(P<0.01),治疗有效率高于对照(P<0.01);②治疗2周后,治疗组神经功能评分较对照组比较差异显著(C表2周、3个月,P<0.01;S表2周、3个月,P<0.01);③治疗组和对照组分别与入院时配伍比较,神经功能评分均有显著差异(P<0.01),表明两种治疗均有疗效。但治疗效果与入院评分不相关(P>0.05);④回归分析表明:神经功能保留情况(3个月时与入院时c评分差值)与年龄、性别及入院时出血量之间均无线性关系。结论:对脑出血(基底节区)进行规范的血压管理是可行的;本次研究中接受规范化血压管理治疗方案的患者更受益。
Objective: To observe the effect of standardized blood pressure management and treatment on the prognosis of acute cerebral hemorrhage (basal ganglia), and to explore the feasibility of staging and standardizing blood pressure management. Methods: The patients with cerebral hemorrhage (basal ganglia) who were hospitalized within 12 hours after onset were randomly assigned to receive the 95th edition of the China Stroke Scale for Clinical Neurological Deficiency (C), Scandinavian Stroke Scale scandinavian stroke scale, SSS, simple S table) mean changes in neurological function scores (admission, 1 week, 2 weeks, 3 months), with “pre-set blood pressure target range” and " (Standard normotensive BPH treatment, n = 41) compared with the control group (n = 41 for normotensive BPM) for 3 months Within the outcome of the change. Results: ①The mortality of the treatment group was lower than that of the control group in 3 months (P <0.01), and the effective rate of treatment was higher than that of the control group (P <0.01); ② After 2 weeks of treatment, the neurological function score of the treatment group was significantly different from that of the control group (P <0.01 in the two weeks of Table C, P <0.01 in the three months of Table C, P <0.01 in the two weeks of S Table, P <0.01); ③The scores of neurological function were significantly different between the treatment group and the control group <0.01), indicating that both treatments are effective. However, the treatment effect was not related to admission score (P> 0.05) .④Regression analysis showed that there was no linear relationship between neurological function retention (difference between c-score at 3 months and admission), age, sex and blood loss on admission relationship. CONCLUSIONS: Standardized blood pressure management for intracerebral hemorrhage (basal ganglia) is feasible; patients in this study who received standardized BP management benefit more.