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目的:探究药学质量监控对临床抗菌治疗疗效的影响。方法:对台州骨伤医院2013年6月~2014年6月期间进行抗菌治疗的80例患者进行研究,对这些患者的临床资料进行回顾分析。将患者随机分成对照组和观察组,每组患者40例。对照组患者未进行临床药学指导用药,而观察组患者在临床药学的指导下用药。对两组患者的治疗效果以及耐药率进行比较分析。结果:对照组患者的耐药率为23.42%,观察组患者的耐药率为5.34%。观察组患者的耐药率明显低于对照组,差异显著具有统计学意义(P<0.05)。观察组患者的治疗有效率为91.22%,对照组患者的治疗有效率为83.54%。对照组患者的治疗有效率明显低于观察组,差异显著具有统计学意义(P<0.05)。结论:在对患者进行抗菌药物治疗时在临床药学的指导下用药,实施药学质量监控,能够有效的降低患者的耐药性,提高治疗效果。
Objective: To investigate the influence of drug quality control on the efficacy of clinical antibacterial therapy. Methods: Eighty patients with antibacterial therapy during Taizhou orthopedic hospital from June 2013 to June 2014 were studied. The clinical data of these patients were retrospectively analyzed. The patients were randomly divided into control group and observation group, 40 cases in each group. Patients in the control group did not receive clinical pharmacy guidance, while patients in the observation group were treated under the guidance of clinical pharmacy. The two groups of patients treated with drug resistance rates were compared. Results: The resistance rate of the control group was 23.42%. The resistance rate of the observation group was 5.34%. The drug resistance rate in observation group was significantly lower than that in control group, the difference was statistically significant (P <0.05). The effective rate of treatment in observation group was 91.22%, while that in control group was 83.54%. The treatment efficiency of the control group was significantly lower than that of the observation group, the difference was statistically significant (P <0.05). Conclusion: When taking antibacterial drug therapy in patients under the guidance of clinical pharmacy, the implementation of pharmaceutical quality control, can effectively reduce the patient’s drug resistance and improve the treatment effect.