有关精神应激诱发冠脉缩窄的研究结果不尽一致,故作者以模拟讲演作为精神应激因子,进一步观察精神应激期间心率、血压和冠脉直径的变化。受试对象男性9例、女性2例,年龄46～67岁。11例中冠脉病变1支或2支者各1例、3支者4例,冠脉无病变者5例。试验前,受试者除心导管检查前肌肉注射安定10mg外,停用所有药物。试验过程中持续监测心电图和血压变化。 The results of studies on stress-induced coronary artery stenosis are not consistent. Therefore, the author uses simulated speech as a stress factor to further observe changes of heart rate, blood pressure and coronary diameter during mental stress. The subjects were 9 males and 2 females, aged 46 to 67 years. In 11 cases, there were 1 case of coronary artery lesion or 2 cases, 4 cases of 3 cases, and 5 cases of non-lesioned coronary artery. Before the test, the subjects discontinued all the drugs except intramuscular injection of 10 mg before catheterization. Continuous monitoring of ECG and blood pressure during the test.