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目的观察雷贝拉唑配合阿莫西林与克拉霉素医治胃溃疡患者的临床效果。方法选取2009年1月-2015年1月收治的胃溃疡患者188例,随机分为研究组与对照组各94例。研究组选取雷贝拉唑配合阿莫西林与克拉霉素治疗,对照组选取枸橼酸铋钾来配合阿莫西林与克拉霉素治疗,比较2组临床效果。结果研究组腹痛缓解率优于对照组,复发率少于对照组,差异有统计学意义(P<0.05)。但2组溃疡愈合的总体有效率与Hp的阴转率相对比,差异无统计学意义(P>0.05)。结论选取雷贝拉唑配合阿莫西林与克拉霉素医治患有胃溃疡的患者,不仅起效较快,腹痛的缓解效率较好,且复发的几率较低,值得在临床中推广及应用。
Objective To observe the clinical efficacy of rabeprazole combined with amoxicillin and clarithromycin in the treatment of patients with gastric ulcer. Methods 188 patients with gastric ulcer admitted from January 2009 to January 2015 were randomly divided into study group and control group, 94 cases each. The study group selected rabeprazole with amoxicillin and clarithromycin treatment, the control group selected bismuth potassium citrate to cooperate with amoxicillin and clarithromycin treatment, the clinical effect of two groups were compared. Results The pain relief rate of the study group was better than that of the control group, and the recurrence rate was lower than that of the control group (P <0.05). However, there was no significant difference between the two groups in the overall effective rate of healing of ulcer and the negative conversion rate of Hp (P> 0.05). Conclusion Rabeprazole combined with amoxicillin and clarithromycin in the treatment of patients with gastric ulcer, not only rapid onset, abdominal pain relief efficiency is good, and the recurrence rate is low, it is worth in the clinical promotion and application.