食管吻合口瘘是食管手术常见而又危险的并发症之一。综合国内文献其发生率约为4～8％,死亡率高达30～50％。本组自1979～1985年间共行食管切除吻合术319例,并发吻合口瘘27例,发生率为8.4％。本文就吻合口瘘发生的原因和预防予以讨论。 Esophageal anastomotic leakage is one of the common and dangerous complications of esophageal surgery. The incidence of comprehensive domestic literature is about 4-8%, and the mortality rate is as high as 30-50%. In this group, 319 cases of esophageal resection and anastomosis were performed from 1979 to 1985, and 27 cases of anastomotic leakage were associated with an 8.4% incidence rate. This article discusses the causes and prevention of anastomotic leakage.