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青霉素族抗菌素引起的急性间质性肾炎(以下简称AIN)已有不少报导。由于甲氧苯青霉素治疗而引起的已超过100例,而青霉素G、氨苄青霉素、苯唑青霉素、乙氧萘青霉素和羧苄青霉素引起的AIN也有报导,新半合成羟氨苄青霉素(Amoxicillin)由于其抗菌效果好,现已得到广泛应用。我们的一个病人在用羟氨苄青霉素治疗过程中发生AIN,简述于下:患者女性42岁,由于发热和皮疹3周而住院。体检身材矮小、盾胸和乳房不发育,在胸骨左缘下方听到Ⅳ级心脏全收缩期杂音,脾触及,下肢有不褪色红斑。实验室检查,白细胞8,900/mm~3,无嗜伊红细
Penicillin antibiotics caused by acute interstitial nephritis (hereinafter referred to as AIN) have been reported. More than 100 cases have been reported due to methicillin treatment, and AIN caused by penicillin G, ampicillin, oxacillin, norcillin and carbenicillin has also been reported. Amoxicillin, a new semi-synthetic amoxicillin, Antibacterial effect, it has been widely used. One of our patients developed AIN during amoxicillin treatment, outlined below: A 42-year-old woman was hospitalized for fever and rash for 3 weeks. Physical short stature, shield chest and breast undeveloped, below the left edge of the sternum to hear Ⅳ heart systolic murmur, spleen touch, lower limbs do not fade erythema. Laboratory tests, leukocytes 8,900 / mm ~ 3, no eosinophilic