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本文研究了Tranilast 对特异抗原诱导的IL-2反应的影响,所得结果如下:Tranilast 的浓度对IL-2反应的影响:在支气管哮喘患儿的末梢血淋巴细胞中添加不同浓度的Tranilast,然后用螨粉(Derma-tophagoides farimae,Df)抗原诱导IL-2反应,发现其抑制效果同浓度有关,而且对粘附细胞和非粘附细胞均有抑制作用,但对粘附细胞抑制效果更强。Tranilast 对Df 及ConA 诱发的支气管哮喘患儿单核细胞IL-2反应的影响:Tranila-
This article studies the effect of Tranilast on IL-2 responses induced by specific antigens. The results obtained are as follows: Effect of Tranilast Concentration on IL-2 Response: Addition of different concentrations of Tranilast to peripheral blood lymphocytes of children with bronchial asthma followed by Derma-tophagoides farimae (Df) antigen induced IL-2 response and found that the inhibitory effect was related to the concentration, but also inhibited both adherent cells and non-adherent cells but inhibited the adherent cells more effectively. Effect of Tranilast on monocyte IL-2 response in Df and ConA-induced asthmatic children: Tranila-