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一些哮喘患者在摄入阿司匹林或其它解热镇痛药后可以诱发哮喘,并被称为阿司匹林哮喘,此类哮喘约占哮喘患者的2.3～20%,其发病机制尚不清。近年来,发现阿司匹林哮喘与阿司匹林等解热镇痛药对前列腺素生物合成的抑制密切相关。本文将扼要介绍这一新进展。
Some patients with asthma can induce asthma after taking aspirin or other antipyretic and analgesic drugs and are referred to as aspirin asthma, which account for about 2.3% to 20% of asthmatic patients. The pathogenesis of asthma is unclear. In recent years, it was found that aspirin asthma and aspirin antipyretic analgesics are closely related to the inhibition of prostaglandin biosynthesis. This article will outline the new progress.