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目的:纵向观察鄱阳湖区血吸虫病重疫区血吸虫病防治效果。方法:采取每年全民化疗结合健康教育的防治策略。此外,在 1996 年血吸虫病易感季节,成年男性加服血吸虫病预防药物青蒿琥酯。结果:居民血吸虫感染率和感染度分别从 1992 年的 26.0% 和 1.92 下降到 1994 年的 10.7% 和 0.55;居民肝、脾肿大,肝实质状况得到显著改善;1995 年夏季试区遭受洪水灾害,居民血吸虫感染率和感染度又上升至18.4%和 1.04;1996 年由于上述防治策略的继续实施及易感季节高危人群口服血吸虫病预防药物青蒿琥酯,居民血吸虫病感染率和感染度又下降至5.0% 和0.25。结论:每年全民化疗结合健康教育与高危人群口服血吸虫病预防药物是控制湖区血吸虫病的一项有效策略。
Objective: To observe longitudinally the effect of schistosomiasis control in severe flooding area of Poyang Lake. Methods: To take annual national chemotherapy combined with health education prevention and control strategies. In addition, in the season of schistosomiasis susceptibility in 1996, adult men received artesunate, a schistosomiasis prevention drug. Results: The infection rate and the infection rate of residents were decreased from 26.0% and 1.92 in 1992 to 10.7% and 0.55 respectively in 1994. The resident liver, spleen enlargement and liver parenchyma were significantly improved. In the summer of 1995, the trial area was flooded. The infection rate and infection rate of residents increased to 18.4% and 1.04 respectively. In 1996, due to the continued implementation of the above-mentioned prevention and control strategies and the prevention of sepsis in elderly people at high risk of seasons, Inositol, the infection rate and the degree of infection of resident schistosomiasis dropped to 5.0% and 0.25 respectively. Conclusion: Every year, chemotherapy combined with health education and oral schistosomiasis prevention in high-risk groups is an effective strategy to control schistosomiasis in the lake.