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在乙型肝炎高流行区,母婴传播是乙型肝炎病毒(HBV)的重要传播方式。HBV母婴传播一般被认为有三条途径:①子宫内传播;②分娩期传播和③产后传播,迄今仅有一些间接的依据提示HBV子宫内传播的可能性。本文以15例HBsAg阳性母亲流产的16例死胎为研究材料,应用血清学、免疫电镜和肝脏免疫组织化学等检测胎儿血清及肝脏中HBV标志,现将实验结果报道如下。一、研究材料选择1983年5～8月间在我校妇产医院住院的中期妊娠的孕妇,采血检测HBsAg(RPHA),
In areas with a high prevalence of hepatitis B, mother-to-infant transmission is an important mode of transmission of hepatitis B virus (HBV). HBV mother-to-child transmission is generally considered to have three pathways: ① intrauterine infection; ② childbirth and ③ postnatal transmission, so far there are only some indirect basis prompted the possibility of HBV intrauterine transmission. In this paper, 15 cases of HBsAg positive mothers miscarriage of 16 stillbirths for the study material, serum, immunoelectron microscopy and liver immunohistochemistry detection of fetal serum and liver HBV markers, the experimental results are reported below. First, the study materials Select May 1983 to August maternity hospital in our hospital pregnant women in the second trimester, blood testing HBsAg (RPHA)