SD雌大鼠从妊娠d 16到分娩后d 21摄取含铅水,断奶后仔鼠仍摄取至出生后d 30,测试仔鼠行为。步下法中,第二次下台潜伏期缩短,5 min内的下台次数增加;水迷宫测试中,通过水迷宫的时间延长,进入盲端的次数增加;且自发活动增强,对新环境的适应性下降。结果表明低剂量铅使幼鼠学习和记忆能力下降,活动增加。 SD female rats from d 16 to d 21 after taking lead-containing water intake, post-weaning pups still up to d 30 after birth, test offspring behavior. In the step-by-step method, the second step down the incubation period was shortened, and the number of steps dropped within 5 minutes was increased. In the water maze test, the number of times of entering the blind end increased by the time of the water maze, and the spontaneous activity increased and the adaptability to the new environment decreased . The results showed that low dose lead to young rats learning and memory ability decline, increased activity.