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目的:观察紫龙双柏油对实验性深Ⅱ度烧伤大鼠的治疗作用。方法:制备实验性大鼠酒精深Ⅱ度烧伤模型,观察使用不同剂量紫龙双柏油对创面愈合时间、创面愈合面积的影响;同时观察其对二甲苯致小鼠耳肿胀、醋酸致小鼠疼痛潜伏期及扭体反应的影响。结果:不同剂量紫龙双柏油均能缩短创面愈合时间,促进创面愈合;并能抑制二甲苯致小鼠耳肿胀,延长醋酸致痛小鼠疼痛潜伏期及疼痛潜伏期,减少其扭体反应次数。结论:紫龙双柏油能促进烧伤创面愈合,并有明显的抗炎、镇痛作用。
Objective: To observe the therapeutic effect of Zilongshengbaodan on experimental deep second degree burn rats. Methods: The experimental rat model of alcohol deep second degree burn was prepared. The effect of different doses of Zilongsan on the wound healing time and area of wound healing was observed. Meanwhile, the effect of xylene on mouse ear swelling and acetic acid-induced mouse pain Latency and writhing response. Results: Different dosages Zilongs double asphalt can shorten the wound healing time and promote wound healing; and can inhibit xylene-induced ear swelling in mice, prolong the pain of acetic acid induced pain in mice incubation period and reduce the number of writhing reaction. Conclusion: Zilong double asphalt can promote burn wound healing, and obvious anti-inflammatory and analgesic effects.