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本研究旨在观察黄芪注射液对冠心病患者红细胞内钠含量和钠转运的影响。67例冠心病患者随机分为黄芪治疗组和对照组。治疗组以黄芪注射液24g 溶于5%葡萄糖液250ml 内静脉滴注,每日1次,共14天;对照组静脉滴注5%葡萄糖液250ml,每日1次,共14天。结果表明,治疗组45例患者的红细胞内钠浓度下降(P<0.01),钠泵活性提高(P<0.01),而对照组无明显变化。提示黄芪具有提高红细胞钠泵活性的作用。
The purpose of this study was to observe the effect of Huangqi Injection on sodium content and sodium transport in patients with coronary heart disease. 67 patients with coronary heart disease were randomly divided into astragalus treatment group and control group. The treatment group was intravenously infused with 250 g of 5% glucose solution in astragalus membranaceus injection 24 g once a day for 14 days. The control group was intravenously infused with 5% glucose 250 ml once daily for 14 days. The results showed that 45 patients in the treatment group had decreased intracellular sodium concentration (P<0.01) and increased sodium pump activity (P<0.01), but no significant changes in the control group. It is suggested that Astragalus has the effect of increasing the activity of sodium pump of red blood cells.