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胎儿子宫内输血可有效地治疗Rh(D)溶血病,但有些胎儿早期病情就很严重,很难进行子宫内输血。最近报告随机试验表明大剂量静注免疫球蛋白(IVIG)可有效地治疗胎儿Rh(D)溶血病。因此作者研究了各种IVIG制品体外抑制单核巨噬细胞吞噬抗Rh(D)抗体包被的红细胞的效果。
Intrauterine fetal blood transfusion can be effective in the treatment of Rh (D) hemolytic disease, but some fetuses early condition is very serious, difficult to transfused intrauterine. Recent reports of randomized trials indicate that high-dose intravenous immunoglobulin (IVIG) is effective in treating fetal Rh (D) hemolytic disease. The authors therefore investigated the effect of various IVIG preparations on inhibiting monocyte-macrophage phagocytosis of anti-Rh (D) antibody-coated erythrocytes in vitro.