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本文运用挤压综合征的动物模型,对肾脏进行了超微结构观察。共用家兔20只,分为单纯致伤组(8只)、肝素治疗组(8只)和正常对照组(4只)。前两组动物于双后肢施以30～34kg压力5小时,造成挤压伤。分别于伤后3、5、7天活体内取肾组织作电镜观察。电镜观察结果:单纯致伤组和肝素治疗组各时相点观察所见基本相同。(1)肾小球:毛细血管内皮细胞肿大,有时增生;前者表现为细胞胞浆增多,富含粗面内质网和游离核蛋白体,高尔基复合体发达,常有微绒毛形成,有时胞浆伸出长而不规则突起,横跨管腔,达于对侧,作架桥状或呈拱桥。有时内皮细胞可见核旁空泡,其内含
In this paper, we use the animal model of crush syndrome to observe the ultrastructure of kidneys. Twenty rabbits were divided into simple injury group (n = 8), heparin treatment group (n = 8) and normal control group (n = 4). The first two groups of animals in the hind limbs impose 30 ~ 34kg pressure for 5 hours, resulting in crush injury. Respectively 3, 5, 7 days after injury to take kidney tissue for electron microscopy. Electron microscopy results: simple injury group and heparin treatment group at each time point observed basically the same. (1) glomerular: capillary endothelial cell swelling, and sometimes hyperplasia; the former showed an increase in cytoplasm, rich in rough endoplasmic reticulum and free ribosomes, developed Golgi complex, often microvilli formation, and sometimes Cytoplasm protruding long and irregular protrusions, across the lumen, up to the contralateral, as a bridge or arch bridge. Sometimes endothelial cells can be seen next to the peritoneal cavity, which contains