农药登记国际协调呼唤GLP实验室

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一、农药登记国际协调 1、世界各国农药管理和农药登记概况目前世界各国的农药管理登记和制度大多数都是建立在本国政策基础之上的。但是各国农药管理和登记的核心内容都是相似的。农药登记资料要求的内容主要是产品化学、残留化学、代谢、哺乳动物毒性、水生生物毒性、对鸟类毒性、对非目标生物的影响及环境归宿等。这些资料可以反映出拟登记产品固有的危害性质及程度,并能反映出人、野生生物及环境对该产品的可能接触量。目前的农药登记一般要求进行多达150~200个不同的试验研究,约需经费5千万至1亿美元。每个国家的管理机构对各种具体的试验研究都规定了标准的试验方法和步骤,但国家之间必然存在着较大的差异。所以各国的研究结 I. International Coordination of Pesticide Registration 1. Overview of Pesticide Management and Pesticide Registration in Various Countries in the World At present, most pesticide management registrations and systems in various countries of the world are based on their own policies. However, the core contents of pesticide administration and registration in all countries are similar. The requirements of pesticide registration information mainly include product chemistry, residual chemistry, metabolism, mammalian toxicity, aquatic toxicity, toxicity to birds, effects on non-target organisms and environmental fate. These data can reflect the nature and extent of the hazards inherent in the product to be registered and reflect the potential exposure of people, wildlife and the environment to the product. The current registration of pesticides generally requires as many as 150-200 different pilot studies, costing between $ 50 million and $ 100 million. The regulatory agencies in each country provide standard test methods and procedures for various specific experimental studies, but there are bound to be major differences between countries. Therefore, the study of various countries
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