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本文总结我室活检诊断恶黑80例,对其临床和病理进行详细分析。结果表明,恶黑主要发生在41-60岁年龄组,占54％,男性:女性1.8:1。皮肤恶黑的发生部位主要在手、脚、头面部、粘膜恶黑发生在鼻腔和眼部,恶黑的发病一般认为与日光照射、损伤、遗传等因素有关。恶黑组织结构复杂,细胞形态多样。多形的瘤细胞排列成肉瘤样,巢状、血管外皮瘤样、腺样等类型。同时也讨论了恶黑的分型、核分裂、浸润深度之间的关系。结节型核分裂最多且浸润深,预后就最差。
This article summarizes the diagnosis of malignant black in 80 cases in our department, and analyzes its clinical and pathological features in detail. The results showed that blackish black mainly occurred in the 41-60 age group, accounting for 54%, male: female 1.8:1. The site of the occurrence of dark skin mainly in the hands, feet, head and face, mucosal black occurs in the nose and eyes, the incidence of evil black is generally believed to be related to sun exposure, injury, genetic and other factors. Black tissue has a complex structure and diverse cellular forms. Polymorphic neoplastic cells are arranged in sarcoma-like, nested, hemangiopericytoma-like, adenoid and other types. At the same time, the relationship between the types of karyotype, nuclear fission, and infiltration depth was also discussed. Nodular karyosclerosis is the most common and deep infiltration, and the prognosis is the worst.