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为探讨乙脑脑脊液免疫球蛋白(Ig)、β_2-微球蛋白(β_2-MG)在小儿脑脊液中的变化及其诊断价值,对50例乙脑患儿做了脑脊液Ig及β_2-MG测定。结果表明:乙脑球儿脑脊液IgG升高33例,占66％。对15例患儿做了β_2-MG测定,升高12例,占80％。说明乙脑患儿脑脊液免疫球蛋白改变以IgG为著,而IgA、IgM不如IgG明显。对15例患儿脑脊液β_2-MG测定升高占80％,而这15例中IgG升高仅占8例,占53.3％。本研究提示,乙脑患儿早期脑脊液中β_2-MG改变比IgG改变更中明显,可做为乙脑患儿早期诊断的建议指标。
To investigate the changes of cerebrospinal fluid immunoglobulin (Ig) and β_2-microglobulin (β_2-MG) in children with cerebrospinal fluid and the diagnostic value of cerebrospinal fluid in cerebrospinal fluid, Ig and β_2-MG of cerebrospinal fluid were measured in 50 children with Igb. The results showed that: Cerebrospinal fluid IgG increased in 33 children (66%). Β_2-MG was measured in 15 children and increased by 12% (80%). Explanations of cerebrospinal fluid immunoglobulin in children with IgE change, and IgA, IgM IgG as obvious. 15 cases of cerebrospinal fluid β_2-MG measured increased 80%, while 15 cases of elevated IgG accounted for only 8 cases, accounting for 53.3%. This study suggests that β_2-MG changes in early cerebrospinal fluid of children with JE are more obvious than those of IgG, which may serve as the recommended indicator for the early diagnosis of JE children.