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目的 探讨孕前肥胖与妊娠期糖尿病 (GDM )之间的关系。方法 采用队列研究对 6 14例孕妇进行调查 ,于孕 2 4～ 2 8周对其进行GDM筛检。结果 孕前体质指数 (BMI)≥ 2 5kg/m2 的人群GDM发病率高于BMI<2 5kg/m2 的人群 ,随孕前腰围增大 ,GDM发病率逐渐升高。非条件Logistic回归分析表明 ,孕前BMI、孕前腰围是GDM重要的有统计学意义的危险因素。结论 孕前肥胖是GDM独立的危险因素 ,控制孕前肥胖是预防GDM发生的重要措施。
Objective To explore the relationship between pre-pregnancy obesity and gestational diabetes mellitus (GDM). Methods A cohort study was conducted on 614 pregnant women and their GDM screening was performed at 24 to 28 weeks of gestation. Results The pre-pregnancy body mass index (BMI) ≥ 25kg / m2 population GDM incidence was higher than the BMI <2.5kg / m2 population, with the pre-pregnancy waist circumference, GDM incidence gradually increased. Non-conditional Logistic regression analysis showed that pre-pregnancy BMI and pre-pregnancy waist circumference are important risk factors of GDM. Conclusion Pre-pregnancy obesity is an independent risk factor for GDM. Pre-pregnancy obesity is an important measure to prevent GDM.