The pharmacokinetics and relative bioavailability were studied in 18 healthy volunteers. A single oral dose of 150 mg irbesartan capsule (test) or tablet (reference) was given to each volunteer according to a randomized 2 way crossover study. The concentrations in plasma were determined by HPLC UV method. The main parameters of irbesartan capsules were: C max : 1.502±0.295 μg/ml, t max : 1.44±0.34 h, t 1/2 : 20.21±14.71 h, AUC 0 t : 11.087±3.443 μg/ml -1 ·h. The relative bioavailability of capsule to tablet was (101.4±28.9) %. The results of statistical analysis showed that two formulations were bioequivalent. The pharmacokinetics and relative bioavailability were studied in 18 healthy volunteers. A single oral dose of 150 mg irbesartan capsule (test) or tablet (reference) was given to each volunteer according to a randomized 2 way crossover study. HPLC UV method. The main parameters of irbesartan capsules were: C max: 1.502 ± 0.295 μg / ml, t max: 1.44 ± 0.34 h, t 1/2: 20.21 ± 14.71 h, AUC 0 t: 11.087 ± 3.443 μg / ml -1 · h. The relative bioavailability of capsule to tablet was (101.4 ± 28.9)%. The results of statistical analysis showed that both two were were bioequivalent.